Aguero, De Bruyne, Sturridge and Gomes in team of the week
Three Man City players and two each from Sunderland and Newcastle feature in this week's selection
Leicester City stumbled, Aston Villa were relegated and Arsenal slumped to fourth as the climax of the Premier League season came another step closer.
Elsewhere around the country, Chelsea can no longer qualify for the Champions League after a comprehensive defeat to Manchester City, while Liverpool's end of season surge continued.
At the bottom of the table, a real dogfight is developing between Newcastle, Sunderland and Norwich, who are separated by just three points after the Magpies won and Sunderland beat Norwich.
But who were the stars of the weekend's action? Here's The Week's pick of the experts' picks:
Goalkeeper: Heurelho Gomes (Watford)
The Watford keeper was a unanimous choice, which is understandable as he saved two penalties as the Hornets beat West Bromwich Albion. "To save one penalty in a game is an achievement but to save two is phenomenal," says Garth Crooks of the BBC. It also makes Gomes the top Fantasy Premier League scorer this weekend, a rare achievement for a keeper.
Defence: Antonio Valencia (Man United), Ramiro Funes Mori (Everton), Nicolas Otamendi (Man City), Jamaal Lascelles (Newcastle)
Back in the Man United team, Valencia gets the nod at full-back after he "put in a fine performance and provided the assist for Marcus Rashford's winner in the 1-0 victory over Aston Villa", says ESPN.
Funes Mori of Everton went one better and scored against Southampton. But he was influential at both ends of the pitch and "made some important interceptions as well as getting on the scoresheet", says the Belfast Telegraph. He is joined by Otamendi of Man City, who was in fine form against Chelsea. "The Argentine barely gave Diego Costa a sniff and showed excellent positional awareness to block Pedro's effort on the line," says Goal.com.
Young Magpie Lascelles has been "thrown into a mess of a Newcastle team and asked to keep them in the division", says ESPN. But the defender "seems to be making the best of what he's been given and put in a fine performance in the 3-0 win over Swansea".
Midfield: Andros Townsend (Newcastle), Lee Cattermole, Fabio Borini (both Sunderland), Kevin de Bruyne (Man City)
Providing the assist for Lascelles's goal was winger Townsend, who also scored as the Magpies beat Swansea. "Andros Townsend may have cost Newcastle a hefty £12m from Tottenham in January, but if the England winger keeps Rafa Benitez's side in the Premier League, the transfer will have been a priceless one," says The Offside Rule website.
Sunderland enforcer Cattermole was at his best against Norwich. He was "like a man possessed", says Crooks of the BBC. "If he wasn't diving into tackles, he was heading and kicking balls off the line." He also makes Harry Redknapp's team of the week in the Daily Telegraph, as he proved himself "a proper leader".
Team-mate Borini also gets the nod. "The Italian was pivotal in a vital away victory for Sam Allardyce's side by scoring a penalty before turning provider for Jermain Defoe's goal," says Goal.com.
Man City missed De Bruyne badly this season when he has been injured and he was very much in the thick of it against Chelsea. He was "all over the pitch, trying to create attacks at every opportunity, and caused Chelsea trouble from the very first whistle", says The Offside Rule.
Attack: Sergio Aguero (Man City), Daniel Sturridge (Liverpool)
De Bruyne and Aguero provided "a glimpse of what life at Manchester City might be like if both... are both fit and firing next season for Pep Guardiola", says ESPN, and Aguero's three goals against Chelsea amounted to "a quality hat trick from the deadliest striker in the Premier League".
Fit-again Sturridge looked close to his best for Liverpool against Bournemouth as he scored one and set up another. "You can't deny that, in the penalty area, there are few strikers better at finishing than the Liverpool man," says the BBC's Crooks.